Prior to implementing any significant change in the use of animals, what is essential for the research team to obtain?

Obtaining IACUC approval for any significant change in the use of animals is essential because the Institutional Animal Care and Use Committee (IACUC) is responsible for overseeing and reviewing all aspects of animal research to ensure ethical and humane treatment. This committee ensures compliance with regulations and guidelines regarding animal welfare, including proper care, housing, and use of animals in research. Before any modifications are made to existing protocols or the introduction of new procedures involving animals, researchers must present their plans to the IACUC for thorough evaluation and approval. This requirement helps to safeguard the animals and uphold the integrity of the research process.

While approval from a funding agency, permission from institutional administration, and written consent from participants may also be important in various contexts of research, they do not replace the specific requirement from the IACUC when it comes to changes involving animal subjects.